Products for Research Use Only
RegisterLogin

ADORA2A Antibody

CAT: 0223-16-289Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-16-289Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes a member of the guanine nucleotide-binding protein (G protein) -coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G (s) and G (olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding.
NCBI Gene ID
135
Swiss Prot
P29274
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ADORA2A (NP_000666.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Immunology, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse heart
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 45kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:1000
Symbol
ADORA2A
Positive Control 2
Rat heart
NCBI Official Name
Adenosine A2a receptor
NCBI Organism
Homo sapiens
Other Product Names
ADORA2A, adenosine A2a receptor, HGNC:263, ADORA2, RDC8, hA2aR, adenosine A2 receptor, adenosine receptor subtype A2a
Tested Applications
WB
Physical Properties
Liquid

Related Products

CatalogName
8111-01mgADORA2B Antibody
8111-01ADORA2B Antibody
8111-002mgADORA2B Antibody
57-724ADORA1 Antibody
43-241ADORA3 Antibody
8111PADORA2B Peptide
43-241PADORA3 Peptide
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody

Alternative Products

CatalogName
GTR18149316ADORA2A Antibody

Popular Products