HEY2 Antibody

• Background:

  This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH) -type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.

• NCBI Gene ID:

  23493

• Swiss Prot:

  Q9UBP5

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HEY2 (NP_036391.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Stem Cell, Transcription

• Purification:

  Affinity purification

• Positive Control:

  A-549

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 36kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  HEY2

• Positive Control 2:

  K562

• Positive Control 3:

  MCF7

• Positive Control 4:

  Mouse brain

• Positive Control 5:

  Rat heart

• NCBI Official Name:

  Hes-related family bHLH transcription factor with YRPW motif 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  HEY2, OTTHUMP00000017138, MGC10720, HRT2, HES-related repressor protein 1, HESR2, HERP1, hairy-related transcription factor 2, hairy/enhancer-of-split related with YRPW motif 2, GRL, GRIDLOCK, CHF1, cardiovascular basic helix-loop-helix factor 1, bHLHb32, BHLHB32, HERP

• Tested Applications:

  WB

• Physical Properties:

  Liquid