HEYL Antibody

• Background:

  This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH) -type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq].

• NCBI Gene ID:

  26508

• Swiss Prot:

  Q9NQ87

• Accession Number:

  Q9NQ87

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This HEYL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human HEYL.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  35 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  HEYL

• NCBI Official Name:

  Hairy/enhancer-of-split related with YRPW motif-like protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kokubo, H., et al. Trends Cardiovasc. Med. 15 (5) :190-194 (2005)

• Background Reference 02:

  Colland, F., et al. Genome Res. 14 (7) :1324-1332 (2004)

• Background Reference 03:

  Iso, T., et al. J. Cell. Physiol. 194 (3) :237-255 (2003)

• Background Reference 04:

  Nakagawa, O., et al. Proc. Natl. Acad. Sci. U.S.A. 97 (25) :13655-13660 (2000)

• Other Product Names:

  Hairy/enhancer-of-split related with YRPW motif-like protein, hHeyL, Class B basic helix-loop-helix protein 33, bHLHb33, Hairy-related transcription factor 3, HRT-3, hHRT3, HEYL, BHLHB33, HRT3

• Tested Applications:

  WB, IF

• Protein ID:

  146286205

• Physical Properties:

  Liquid