ITGAX Antibody

• Background:

  This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4) . The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  3687

• Swiss Prot:

  P20702

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 100-350 of human ITGAX (NP_000878.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Immunology, Signal Transduction, Stem Cell

• Purification:

  Affinity purification

• Positive Control:

  THP-1

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 150kDa

• Fragment:

  IgG

• Symbol:

  ITGAX

• Positive Control 2:

  Mouse small intestine

• Positive Control 3:

  Mouse spleen

• NCBI Official Name:

  Integrin, alpha X (complement component 3 receptor 4 subunit)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150, CD11c, ITGAX, CD11C

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid