FUT3 Antibody

• Background:

  The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha (1,3) -fucosyltransferase and alpha (1,4) -fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.

• NCBI Gene ID:

  2525

• Swiss Prot:

  P21217

• Host:

  Rabbit

• Reactivity:

  Human, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FUT3 (NP_000140.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  Affinity purification

• Positive Control:

  A-549

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 50kDa

• Fragment:

  IgG

• Symbol:

  FUT3

• Positive Control 2:

  HT-29

• Positive Control 3:

  293T

• Positive Control 4:

  LO2

• NCBI Official Name:

  Galactoside 3 (4) -L-fucosyltransferase

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Galactoside 3 (4) -L-fucosyltransferase, Blood group Lewis alpha-4-fucosyltransferase, Lewis FT, Fucosyltransferase 3, Fucosyltransferase III, FucT-III, FUT3, FT3B, LE

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid