DRD3 Antibody

• Background:

  This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD) .

• NCBI Gene ID:

  1814

• Swiss Prot:

  P35462

• Host:

  Rabbit

• Reactivity:

  Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DRD3 (NP_000787.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  Affinity purification

• Positive Control:

  Mouse brain

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 44kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  DRD3

• Positive Control 2:

  Rat brain

• NCBI Official Name:

  Dopamine receptor D3

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  DRD3, D3 dopamine receptor, D3DR, Dopamine 3 receptor, Dopamine receptor D3, D3nf, Essential tremor 1, ETM1, FET1, D (3) dopamine receptor, Dopamine D3 receptor

• Tested Applications:

  WB

• Physical Properties:

  Liquid