DRD2 Antibody

• Background :

  This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.

• NCBI Gene ID :

  1813

• Swiss Prot :

  P14416

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 214-373 of human DRD2 (NP_000786.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Neuroscience, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  A-549

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 54kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:500 - 1:1000

• Symbol :

  DRD2

• Positive Control 2 :

  Mouse brain

• Positive Control 3 :

  Rat brain

• NCBI Official Name :

  D (2) dopamine receptor

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  D (2) dopamine receptor, Dopamine D2 receptor, DRD2

• Tested Applications :

  WB

• Physical Properties :

  Liquid