DRD4 Antibody

• Background :

  This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.

• NCBI Gene ID :

  1815

• Swiss Prot :

  P21917

• Host :

  Rabbit

• Reactivity :

  Mouse, Rat

• Immunogen :

  A synthetic peptide corresponding to a sequence within amino acids 100-200 of human DRD4 (NP_000788.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Neuroscience

• Purification :

  Affinity purification

• Positive Control :

  Mouse brain

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 52kDa

• Fragment :

  IgG

• Symbol :

  DRD4

• Positive Control 2 :

  Rat brain

• NCBI Official Name :

  Dopamine receptor D4

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  DRD4, dopamine receptor D4, D4DR, D (2C) dopamine receptor, dopamine D4 receptor, seven transmembrane helix receptor

• Tested Applications :

  WB, IHC

• Physical Properties :

  Liquid