DRD4 Antibody

• Background:

  This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.

• NCBI Gene ID:

  1815

• Swiss Prot:

  P21917

• Host:

  Rabbit

• Reactivity:

  Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 100-200 of human DRD4 (NP_000788.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  Affinity purification

• Positive Control:

  Mouse brain

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 52kDa

• Fragment:

  IgG

• Symbol:

  DRD4

• Positive Control 2:

  Rat brain

• NCBI Official Name:

  Dopamine receptor D4

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  DRD4, dopamine receptor D4, D4DR, D (2C) dopamine receptor, dopamine D4 receptor, seven transmembrane helix receptor

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid