PHC2 Antibody

• Background :

  In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID :

  1912

• Swiss Prot :

  Q8IXK0

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 250-323 of human PHC2 (NP_004418.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Affinity purification

• Positive Control :

  DU145

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 45kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:500 - 1:2000

• Symbol :

  PHC2

• Positive Control 2 :

  HT-29

• Positive Control 3 :

  HeLa

• Positive Control 4 :

  Jurkat

• Positive Control 5 :

  293T

• NCBI Official Name :

  Polyhomeotic homolog 2

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  EDR2, HPH2, PH2, polyhomeotic-like protein 2, early development regulator 2 (homolog of polyhomeotic 2), early development regulatory protein 2, polyhomeotic 2, polyhomeotic-like 2

• Tested Applications :

  WB

• Physical Properties :

  Liquid