CAPN9 Antibody

CAT: 0223-15-200Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-15-200Size:100 µL
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Background
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
10753
Swiss Prot
O14815
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 391-690 of human CAPN9 (NP_006606.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
SGC-7901
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 79kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
CAPN9
Positive Control 2
HL-60
Positive Control 3
HT-29
Positive Control 4
Mouse stomach
Positive Control 5
Mouse small intestine
Positive Control 6
Rat stomach
NCBI Official Name
Calpain-9
NCBI Organism
Homo sapiens
Other Product Names
Calpain-9, 3422-, Digestive tract-specific calpain, New calpain 4, nCL-4, Protein CG36, CAPN9, NCL4
Tested Applications
WB
Physical Properties
Liquid

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