CAPN8 Antibody

• Background:

  Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta-subunit of coatomer complex (By similarity) .

• NCBI Gene ID:

  388743

• Swiss Prot:

  A6NHC0

• Accession Number:

  A6NHC0

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CAPN8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-318 amino acids from the Central region of human CAPN8.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  79 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CAPN8

• NCBI Official Name:

  Calpain-8

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hata, S., et al. J. Biol. Chem. 282 (38) :27847-27856 (2007)

• Background Reference 02:

  Oh, J.H., et al. Mamm. Genome 16 (12) :942-954 (2005)

• Background Reference 03:

  Hata, S., et al. J. Mol. Evol. 53 (3) :191-203 (2001)

• Background Reference 04:

  Huang, Y., et al. Trends Mol Med 7 (8) :355-362 (2001)

• Other Product Names:

  Calpain-8, New calpain 2, nCL-2, Stomach-specific M-type calpain, CAPN8, NCL2

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid