CAPN8 Antibody

• Background :

  Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta-subunit of coatomer complex (By similarity) .

• NCBI Gene ID :

  388743

• Swiss Prot :

  A6NHC0

• Accession Number :

  A6NHC0

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This CAPN8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-318 amino acids from the Central region of human CAPN8.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  79 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  CAPN8

• NCBI Official Name :

  Calpain-8

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Hata, S., et al. J. Biol. Chem. 282 (38) :27847-27856 (2007)

• Background Reference 02 :

  Oh, J.H., et al. Mamm. Genome 16 (12) :942-954 (2005)

• Background Reference 03 :

  Hata, S., et al. J. Mol. Evol. 53 (3) :191-203 (2001)

• Background Reference 04 :

  Huang, Y., et al. Trends Mol Med 7 (8) :355-362 (2001)

• Other Product Names :

  Calpain-8, New calpain 2, nCL-2, Stomach-specific M-type calpain, CAPN8, NCL2

• Tested Applications :

  WB, IHC-P

• Physical Properties :

  Liquid