MDFI Antibody

• Background:

  This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.

• NCBI Gene ID:

  4188

• Swiss Prot:

  Q99750

• Host:

  Rabbit

• Reactivity:

  Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human MDFI (NP_005577.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  Mouse heart

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 35kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  MDFI

• Positive Control 2:

  Rat heart

• NCBI Official Name:

  MyoD family inhibitor

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  MDFI, inhibitor of MyoD family a, OTTHUMP00000196414, OTTHUMP00000016375, I-mfa, I-MF, MyoD family inhibitor, MDFI

• Tested Applications:

  WB

• Physical Properties:

  Liquid