SUFU Antibody

• Background:

  The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  51684

• Swiss Prot:

  Q9UMX1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 325-484 of human SUFU (NP_057253.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cancer, Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  Mouse testis

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 54kDa

• Fragment:

  IgG

• Symbol:

  SUFU

• Positive Control 2:

  Rat kidney

• NCBI Official Name:

  Suppressor of fused homolog (Drosophila)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  SUFUH, SUFUXL, PRO1280, CFL, SUFUH

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid