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Sufu (phospho Ser342) Antibody

CAT: 0223-79-513Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-79-513Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SUFU encodes a component of the Sonic hedgehog (SHH; MIM 600725) /Patched (PTCH; MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945; BCNS, MIM 109400; and GCPS, MIM 175700)
NCBI Gene ID
51684
Swiss Prot
Q9UMX1
Accession Number
NP_057253.2
Host
Rabbit
Reactivity
Human
Immunogen
Sufu (Phospho-Ser342) antibody was raised against a peptide sequence around phosphorylation site of Serine 342 (A-P-S (p) -R-K) derived from Human Sufu.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Phospho-Specific
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Phospho-Specific
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
54 kDa
Specificity
This antibody detects endogenous level of Sufu protein only when phosphorylated at serine 342.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
SUFU
NCBI Official Name
Suppressor of fused homolog (Drosophila)
NCBI Organism
Homo sapiens
Background Reference 01
Zimmern P, et al. (2010) Neurourol Urodyn. 29 (5) : 715-8. Wang C, et al. (2010) Development. 137 (12) : 2001-9. Rabasseda X. et al. (2010) Drug News Perspect. 23 (4) : 273-5.
Other Product Names
SUFUH, SUFUXL, PRO1280, CFL, SUFUH
Tested Applications
WB
Protein ID
19923479
Physical Properties
Liquid

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