ECH1 Antibody

• Background :

  This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.

• NCBI Gene ID :

  1891

• Swiss Prot :

  Q13011

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-328 of human ECH1 (NP_001389.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  A375

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 36kDa

• Fragment :

  IgG

• Symbol :

  ECH1

• Positive Control 2 :

  BxPC-3

• Positive Control 3 :

  HepG2

• Positive Control 4 :

  Jurkat

• Positive Control 5 :

  MCF7

• Positive Control 6 :

  K-562

• NCBI Official Name :

  Enoyl CoA hydratase 1, peroxisomal

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  ECH1, HPXEL

• Tested Applications :

  WB, IHC

• Physical Properties :

  Liquid