MTCH2 Antibody

• Background:

  This gene encodes a member of the SLC25 family of nuclear-encoded transporters that are localized in the inner mitochondrial membrane. Members of this superfamily are involved in many metabolic pathways and cell functions. Genome-wide association studies in human have identified single-nucleotide polymorphisms in several loci associated with obesity. This gene is one such locus, which is highly expressed in white adipose tissue and adipocytes, and thought to play a regulatory role in adipocyte differentiation and biology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA can give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon.

• NCBI Gene ID:

  23788

• Swiss Prot:

  Q9Y6C9

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 30-175 of human MTCH2 (NP_055157.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cancer, Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HepG2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 33kDa

• Fragment:

  IgG

• Symbol:

  MTCH2

• Positive Control 2:

  HeLa

• Positive Control 3:

  293T

• Positive Control 4:

  HT-29

• Positive Control 5:

  Mouse small intestine

• Positive Control 6:

  Mouse brain

• NCBI Official Name:

  Mitochondrial carrier homolog 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Mitochondrial carrier homolog 2, Met-induced mitochondrial protein, MTCH2, MIMP

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid