AASS Antibody

• Background:

  This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.

• NCBI Gene ID:

  10157

• Swiss Prot:

  Q9UDR5

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 180-400 of human AASS (NP_005754.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  293T

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 102kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  AASS

• Positive Control 2:

  Mouse kidney

• Positive Control 3:

  Mouse liver

• Positive Control 4:

  Mouse heart

• Positive Control 5:

  Mouse brain

• Positive Control 6:

  Rat kidney

• NCBI Official Name:

  Alpha-aminoadipic semialdehyde synthase, mitochondrial

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Alpha-aminoadipic semialdehyde synthase, mitochondrial, LKR/SDH, Lysine ketoglutarate reductase, LKR, LOR, Saccharopine dehydrogenase, SDH, AASS

• Tested Applications:

  WB

• Physical Properties:

  Liquid