AASS Antibody

• Background :

  This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.

• NCBI Gene ID :

  10157

• Swiss Prot :

  Q9UDR5

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 180-400 of human AASS (NP_005754.2) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  293T

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 102kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:500 - 1:2000

• Symbol :

  AASS

• Positive Control 2 :

  Mouse kidney

• Positive Control 3 :

  Mouse liver

• Positive Control 4 :

  Mouse heart

• Positive Control 5 :

  Mouse brain

• Positive Control 6 :

  Rat kidney

• NCBI Official Name :

  Alpha-aminoadipic semialdehyde synthase, mitochondrial

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  Alpha-aminoadipic semialdehyde synthase, mitochondrial, LKR/SDH, Lysine ketoglutarate reductase, LKR, LOR, Saccharopine dehydrogenase, SDH, AASS

• Tested Applications :

  WB

• Physical Properties :

  Liquid