AASS Antibody

• Background :

  This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.

• NCBI Gene ID :

  10157

• Swiss Prot :

  Q9UDR5

• Accession Number :

  Q9UDR5

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This AASS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 805-834 amino acids from the C-terminal region of human AASS.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Obesity, Signal Transduction

• Purification :

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  102 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  AASS

• NCBI Official Name :

  Alpha-aminoadipic semialdehyde synthase, mitochondrial

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Sacksteder, K.A., et al. Am. J. Hum. Genet. 66 (6) :1736-1743 (2000)

• Background Reference 02 :

  Papes, F., et al. Biochem. J. 344 PT 2, 555-563 (1999) :

• Other Product Names :

  Alpha-aminoadipic semialdehyde synthase, mitochondrial, LKR/SDH, Lysine ketoglutarate reductase, LKR, LOR, Saccharopine dehydrogenase, SDH, AASS

• Tested Applications :

  WB, Flow

• Protein ID :

  46396032

• Physical Properties :

  Liquid