AASS Antibody

• Background:

  This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.

• NCBI Gene ID:

  10157

• Swiss Prot:

  Q9UDR5

• Accession Number:

  Q9UDR5

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This AASS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 805-834 amino acids from the C-terminal region of human AASS.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  102 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  AASS

• NCBI Official Name:

  Alpha-aminoadipic semialdehyde synthase, mitochondrial

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Sacksteder, K.A., et al. Am. J. Hum. Genet. 66 (6) :1736-1743 (2000)

• Background Reference 02:

  Papes, F., et al. Biochem. J. 344 PT 2, 555-563 (1999) :

• Other Product Names:

  Alpha-aminoadipic semialdehyde synthase, mitochondrial, LKR/SDH, Lysine ketoglutarate reductase, LKR, LOR, Saccharopine dehydrogenase, SDH, AASS

• Tested Applications:

  WB, Flow

• Protein ID:

  46396032

• Physical Properties:

  Liquid