GBA2 Antibody

• Background:

  This gene encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds. Studies to determine subcellular localization of this protein in the liver indicated that the enzyme was mainly enriched in the microsomal fraction where it appeared to be confined to the endoplasmic reticulum. This putative transmembrane protein is thought to play a role in carbohydrate transport and metabolism.

• NCBI Gene ID:

  57704

• Swiss Prot:

  Q9HCG7

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 708-927 of human GBA2 (NP_065995.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  U-87MG

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 105kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  GBA2

• Positive Control 2:

  Mouse kidney

• Positive Control 3:

  Mouse heart

• NCBI Official Name:

  Glucosylceramidase beta 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  AD035, NLGase, SPG46, non-lysosomal glucosylceramidase, beta-glucocerebrosidase 2, bile acid beta-glucosidase GBA2, bile acid glucosyl transferase GBA2, cholesterol glucosyltransferase GBA2, cholesteryl-beta-glucosidase GBA2, glucosidase, beta (bile acid) 2, glucosylceramidase 2

• Tested Applications:

  WB

• Physical Properties:

  Liquid