PARD6A Antibody

• Background :

  This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

• NCBI Gene ID :

  50855

• Swiss Prot :

  Q9NPB6

• Host :

  Rabbit

• Reactivity :

  Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 256-345 of human PARD6A (NP_001032358.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Cell Cycle, Signal Transduction, Stem Cell

• Purification :

  Affinity purification

• Positive Control :

  Rat skeletal muscle

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 37kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:500 - 1:2000

• Symbol :

  PARD6A

• NCBI Official Name :

  Par-6 family cell polarity regulator alpha

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  PARD6A, PAR-6, TAX40, PAR-6A, TIP-40, PAR6alpha, par-6 partitioning defective 6 homolog alpha (C.elegans), Tax interaction protein 40, par-6 (partitioning defective 6, C.elegans) homolog alpha, PAR6A

• Tested Applications :

  WB

• Physical Properties :

  Liquid