PARD3 Antibody

• Background:

  PARD proteins, which were first identified in C. elegans, are essential for asymmetric cell division and polarized growth, whereas CDC42 (MIM 116952) mediates the establishment of cell polarity. The CDC42 GTPase, which is controlled by nucleotide exchange factors (GEFs; see MIM 606057) and GTPase-activating proteins (GAPs; see MIM 604980), interacts with a large set of effector proteins that typically contain a CDC42/RAC (MIM 602048) -interactive binding (CRIB) domain.

• NCBI Gene ID:

  56288

• Swiss Prot:

  Q8TEW0

• Accession Number:

  Q8TEW0

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This PARD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1329-1356 amino acids from the C-terminal region of human PARD3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  151 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PARD3

• NCBI Official Name:

  Partitioning defective 3 homolog

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Noda, Y., et.al., Genes Cells (2), 107-119 (2001)

• Background Reference 02:

  Beausoleil, S.A., et.al., Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 (2004)

• Other Product Names:

  Partitioning defective 3 homolog, PAR-3, PARD-3, Atypical PKC isotype-specific-interacting protein, ASIP, CTCL tumor antigen se2-5, PAR3-alpha, PARD3, PAR3, PAR3A

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  30913162

• Physical Properties:

  Liquid