CUL4B Antibody

• Background:

  This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  8450

• Swiss Prot:

  Q13620

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-152 of human CUL4B (NP_003579.3) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  LO2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 110kDa

• Fragment:

  IgG

• Symbol:

  CUL4B

• Positive Control 2:

  SH-SY5Y

• Positive Control 3:

  HeLa

• Positive Control 4:

  Mouse brain

• Positive Control 5:

  Mouse testis

• Positive Control 6:

  Mouse liver

• NCBI Official Name:

  Cullin-4B

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Cullin-4B, CUL-4B, CUL4B, KIAA0695

• Tested Applications:

  WB, IP

• Physical Properties:

  Liquid