USH1C Antibody

• Background:

  This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  10083

• Swiss Prot:

  Q9Y6N9

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 264-533 of human USH1C (NP_001284693.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cell Cycle, Neuroscience

• Purification:

  Affinity purification

• Positive Control:

  293T

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 62kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  USH1C

• Positive Control 2:

  HeLa

• Positive Control 3:

  Mouse kidney

• Positive Control 4:

  Mouse small intestine

• Positive Control 5:

  Rat kidney

• NCBI Official Name:

  Usher syndrome 1C (autosomal recessive, severe)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  USH1C, AIE-75, DFNB18, PDZ-45, PDZ-73, HARMONIN, NY-CO-37, NY-CO-38, PDZ-73/NY-CO-38, Usher syndrome 1C (autosomal recessive, severe), harmonin, PDZ-73 protein, ush1cpst, deafness, autosomal recessive 18, AIE75

• Tested Applications:

  WB

• Physical Properties:

  Liquid