PRMT7 Antibody

• Background:

  This gene encodes a member of the protein arginine N-methyltransferase family of proteins. The encoded enzyme transfers single methyl groups to arginine residues to generate monomethylarginines on histone proteins as well as other protein substrates. This enzyme plays a role in a wide range of biological processes, including neuronal differentiation, male germ line imprinting, small nuclear ribonucleoprotein biogenesis, and regulation of the Wnt signaling pathway. Mutations in this gene underlie multiple related syndromes in human patients characterized by intellectual disability, short stature and other features. The encoded protein may promote breast cancer cell invasion and metastasis in human patients.

• NCBI Gene ID:

  54496

• Swiss Prot:

  Q9NVM4

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 513-692 of human PRMT7 (NP_061896.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  U-87MG

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 75kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  PRMT7

• Positive Control 2:

  HeLa

• Positive Control 3:

  MCF7

• Positive Control 4:

  Mouse testis

• Positive Control 5:

  Rat testis

• NCBI Official Name:

  Protein arginine methyltransferase 7

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  [Myelin basic protein]-arginine N-methyltransferase PRMT7, FLJ10640, histone-arginine N-methyltransferase PRMT7, KIAA1933, myelin basic protein-arginine N-methyltransferase, OTTHUMP00000174863, PRMT7, protein arginine methyltransferase 7, protein arginine N-methyltransferase 7

• Tested Applications:

  WB

• Physical Properties:

  Liquid