STAT1 Antibody

• Background:

  The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

• NCBI Gene ID:

  6772

• Swiss Prot:

  P42224

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 650-750 of human STAT1 (NP_009330.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cancer, Cell Cycle, Immunology, Signal Transduction, Transcription, Inflammasomes

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 91kDa

• Fragment:

  IgG

• Symbol:

  STAT1

• NCBI Official Name:

  Signal transducer and activator of transcription 1, 91kDa

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  STAT1 alpha Antibody: CANDF7, ISGF-3, STAT91

• Tested Applications:

  WB, IHC, IF, IP

• Physical Properties:

  Liquid