Products for Research Use Only

TG Antibody

CAT: 0223-14-109Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-14-109Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.
NCBI Gene ID
7038
Swiss Prot
P01266
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 2469-2768 of human TG (NP_003226.4) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Growth Factors, Signal Transduction
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 290kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
TG
NCBI Official Name
Thyroglobulin
NCBI Organism
Homo sapiens
Other Product Names
TG, AITD3, TDH3, Thyroglobulin, TGN
Tested Applications
WB
Physical Properties
Liquid