LGR5 Antibody

• Background :

  The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID :

  8549

• Swiss Prot :

  O75473

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 824-907 of human LGR5 (NP_003658.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Signal Transduction, Stem Cell

• Purification :

  Affinity purification

• Positive Control :

  HT-29

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 105kDa

• Fragment :

  IgG

• Symbol :

  LGR5

• Positive Control 2 :

  HepG2

• Positive Control 3 :

  SKOV3

• Positive Control 4 :

  A-431

• Positive Control 5 :

  Mouse brain

• Positive Control 6 :

  Rat brain

• NCBI Official Name :

  Leucine-rich repeat-containing G-protein coupled receptor 5

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  Leucine-rich repeat-containing G-protein coupled receptor 5, G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38, LGR5, GPR49, GPR67

• Tested Applications :

  WB, IF

• Physical Properties :

  Liquid