Products for Research Use Only
RegisterLogin

SMAD7 Antibody

CAT: 0223-13-698Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-13-698Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3) . Several transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
4092
Swiss Prot
O15105
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 220-390 of human SMAD7 (NP_005895.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
SW480
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 46kDa
Fragment
IgG
Symbol
SMAD7
NCBI Official Name
SMAD family member 7
NCBI Organism
Homo sapiens
Other Product Names
SMAD7, CRCS3, MADH7, MADH8
Tested Applications
WB, IF
Physical Properties
Liquid

Related Products

CatalogName
23-013SMAD2/SMAD3 Antibody
23-014SMAD2/SMAD3 Antibody
31-167SMAD6 Antibody
57-106SMAD3 Antibody
15-704SMAD6 Antibody
27-476SMAD5 Antibody
27-475SMAD5 Antibody
27-474SMAD4 Antibody
63-183SMAD4 Antibody
14-031SMAD3 Antibody

Alternative Products

CatalogName
GTR18101091SMAD7 Antibody

Popular Products