MEGF10 Antibody

• Background:

  This gene encodes a member of the multiple epidermal growth factor-like domains protein family. The encoded protein plays a role in cell adhesion, motility and proliferation, and is a critical mediator of apoptotic cell phagocytosis as well as amyloid-beta peptide uptake in the brain. Expression of this gene may be associated with schizophrenia, and mutations in this gene are a cause of early-onset myopathy, areflexia, respiratory distress, and dysphagia (EMARDD) as well as congenital myopathy with minicores. Alternatively spliced transcript variants have been observed for this gene.

• NCBI Gene ID:

  84466

• Swiss Prot:

  Q96KG7

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 26-160 of human MEGF10 (NP_001295048.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cell Cycle, Stem Cell

• Purification:

  Affinity purification

• Positive Control:

  U-251MG

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 122kDa

• Fragment:

  IgG

• Symbol:

  MEGF10

• Positive Control 2:

  HT-29

• Positive Control 3:

  MCF7

• Positive Control 4:

  Mouse brain

• Positive Control 5:

  Mouse liver

• Positive Control 6:

  Rat brain

• NCBI Official Name:

  Multiple EGF like domains 10

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  EMARDD, multiple epidermal growth factor-like domains protein 10

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid