Anti-MEGF10 Antibody

Boster Bio Anti-MEGF10 Antibody catalog # A06799. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Multiple epidermal growth factor-like domains protein 10

MEGF10

Q96KG7

Human, Mouse, Rat

Recombinant fusion protein of human MEGF10 (NP_115822.1) .

WB

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

WB: 1:500-1:2000

Liquid

Membrane receptor involved in phagocytosis by macrophages and astrocytes of apoptotic cells. Receptor for C1q, an eat-me signal, that binds phosphatidylserine expressed on the surface of apoptotic cells (PubMed:27170117) . Cooperates with ABCA1 within the process of engulfment. Promotes the formation of large intracellular vacuoles and may be responsible for the uptake of amyloid-beta peptides (PubMed:20828568, PubMed:17643423) . Necessary for astrocyte-dependent apoptotic neuron clearance in the developing cerebellum (PubMed:27170117) . Plays role in muscle cell proliferation, adhesion and motility. Is also an essential factor in the regulation of myogenesis. Controls the balance between skeletal muscle satellite cells proliferation and differentiation through regulation of the notch signaling pathway (PubMed:28498977) . May also function in the mosaic spacing of specific neuron subtypes in the retina through homotypic retinal neuron repulsion. Mosaics provide a mechanism to distribute each cell type evenly across the retina, ensuring that all parts of the visual field have access to a full set of processing elements (PubMed:17498693, PubMed:17643423, PubMed:20828568, PubMed:22101682, PubMed:27170117, PubMed:28498977) .

122205 MW

Available

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Multiple epidermal growth factor-like domains protein 10

Cell membrane