TMEFF2 Antibody

• Background:

  This gene encodes a member of the tomoregulin family of transmembrane proteins. This protein has been shown to function as both an oncogene and a tumor suppressor depending on the cellular context and may regulate prostate cancer cell invasion. Multiple soluble forms of this protein have been identified that arise from both an alternative splice variant and ectodomain shedding. Additionally, this gene has been found to be hypermethylated in multiple cancer types. Alternative splicing results in multiple transcript variants.

• NCBI Gene ID:

  23671

• Swiss Prot:

  Q9UIK5

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 41-320 of human TMEFF2 (NP_057276.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Growth Factors

• Purification:

  Affinity purification

• Positive Control:

  U-87MG

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 41kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  TMEFF2

• Positive Control 2:

  A-549

• Positive Control 3:

  SW480

• Positive Control 4:

  HeLa

• Positive Control 5:

  Mouse brain

• Positive Control 6:

  Mouse lung

• NCBI Official Name:

  Transmembrane protein with EGF like and two follistatin like domains 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CT120.2, HPP1, TENB2, TPEF, TR, TR-2, tomoregulin-2, cancer/testis antigen family 12member 2, hyperplastic polyposis protein 1, transmembrane protein TENB2, transmembrane protein with EGF-like and two follistatin-like domains

• Tested Applications:

  WB

• Physical Properties:

  Liquid