Hexokinase II Antibody

• Background:

  Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

• NCBI Gene ID:

  3099

• Swiss Prot:

  P52789

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human Hexokinase II (NP_000180.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  293T

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 102kDa

• Fragment:

  IgG

• Symbol:

  HK2

• Positive Control 2:

  K-562

• Positive Control 3:

  HL-60

• NCBI Official Name:

  Hexokinase 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  HK2, DKFZp686M1669, HKII, HXK2

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid