HSP90B1 Antibody

• Background:

  This gene encodes a member of a family of adenosine triphosphate (ATP) -metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15.

• NCBI Gene ID:

  7184

• Swiss Prot:

  P14625

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 550-650 of human HSP90B1 (NP_003290.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cancer, Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  A375

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 110kDa

• Fragment:

  IgG

• Symbol:

  HSP90B1

• Positive Control 2:

  HeLa

• Positive Control 3:

  LO2

• Positive Control 4:

  NIH/3T3

• Positive Control 5:

  Mouse liver

• NCBI Official Name:

  Heat shock protein 90kDa beta (Grp94), member 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  HSP90B1, ECGP, GP96, TRA1, GRP94, HEL35, HEL-S-125m

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid