HDAC5 Antibody

CAT: 0223-13-228Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-13-228Size:100 µL
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
10014
Swiss Prot
Q9UQL6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 550-650 of human HDAC5 (NP_005465.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Immunology, Signal Transduction, Stem Cell
Purification
Affinity purification
Positive Control
SW620
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 132kDa
Fragment
IgG
Symbol
HDAC5
Positive Control 2
Mouse brain
Positive Control 3
Mouse heart
Positive Control 4
Rat brain
Positive Control 5
Rat heart
NCBI Official Name
Histone deacetylase 5
NCBI Organism
Homo sapiens
Other Product Names
HD5, NY-CO-9, NFKB3, HD5
Tested Applications
WB, IHC, IF
Physical Properties
Liquid

Alternative Products

Popular Products