PSME3 Antibody

CAT: 0223-13-119Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-13-119Size:100 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Alternate splicing results in multiple transcript variants.
NCBI Gene ID
10197
Swiss Prot
P61289
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-254 of human PSME3 (NP_789839.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 32kDa
Fragment
IgG
Symbol
PSME3
Positive Control 2
PC-12
NCBI Official Name
Proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
NCBI Organism
Homo sapiens
Other Product Names
PSME3, Ki, PA28-gamma, PA28G, REG-GAMMA, HEL-S-283, PA28gamma
Tested Applications
WB, IF
Physical Properties
Liquid

Related Products

CatalogName
96-941PSME3 Recombinant Protein
62-405PSME2 Antibody
61-858PSME1 Antibody
62-406PSME2 Antibody
27-143PSMC3 Antibody
27-088PSMB3 Antibody
18-814PSMD3 Antibody
15-216PSME4 Antibody
46-239PSME2 Antibody
15-112PSME2 Antibody

Alternative Products

CatalogName
OAGA00529-100ULPSME3 antibody

Popular Products