ITGB3 Antibody

• Background:

  The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

• NCBI Gene ID:

  3690

• Swiss Prot:

  P05106

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 609-788 of human ITGB3 (NP_000203.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Immunology, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HepG2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 112kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  ITGB3

• Positive Control 2:

  DU145

• Positive Control 3:

  HT-1080

• Positive Control 4:

  PC-3

• Positive Control 5:

  Mouse liver

• Positive Control 6:

  Rat liver

• NCBI Official Name:

  Integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Integrin beta-3, Platelet membrane glycoprotein IIIa, GPIIIa, CD61, ITGB3, GP3A

• Tested Applications:

  WB

• Physical Properties:

  Liquid