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PRMT2 Antibody

CAT: 0223-55-014Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-55-014Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.
NCBI Gene ID
3275
Swiss Prot
P55345
Accession Number
P55345
Host
Rabbit
Reactivity
Human
Immunogen
This PRMT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-53 amino acids from the N-terminal region of human PRMT2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
49 kDa
Fragment
Rabbit Ig
Symbol
PRMT2
NCBI Official Name
Protein arginine N-methyltransferase 2
NCBI Organism
Homo sapiens
Background Reference 01
Qi, C., et al., J. Biol. Chem. 277 (32) :28624-28630 (2002) .
Background Reference 02
Scott, H.S., et al., Genomics 48 (3) :330-340 (1998) .
Background Reference 03
Katsanis, N., et al., Mamm. Genome 8 (7) :526-529 (1997) .
Other Product Names
Protein arginine N-methyltransferase 2, 211-, Histone-arginine N-methyltransferase PRMT2, PRMT2, HMT1, HRMT1L1
Tested Applications
WB, IHC-P
Protein ID
2499805
Physical Properties
Liquid

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