CHADL Antibody

• Background:

  The Chondroadherin-like (CHADL) protein, also known as SLRR4B, is homologous to the Chondroadherin protein and is expressed cartillaginous tissues (1) . Like Chondroadherin, CHADL belongs to the small leucine-rich proteoglycan (SLRP) family and class IV subfamily and plays a significant role in the regulation of chondrocyte growth and proliferation (1,2) . CHADL is thought to play a negative regualtory role in collagen fibrillogenesis and chondrocyte differentiation (1) .

• NCBI Gene ID:

  150356

• Swiss Prot:

  Q6NUI6

• Accession Number:

  NP_612490

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Stem Cell, Homeostasis

• Purification:

  CHADL Antibody is affinity chromatography purified via peptide column.

• Positive Control:

  Cat. No. 1467 - Rat Skeletal Muscle Tissue Lysate

• Concentration:

  1 mg/mL

• Buffer:

  CHADL Antibody is supplied in PBS containing 0.02% sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  CHADL antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

• Fragment:

  IgG

• Specificity:

  CHADL antibody is human, mouse and rat reactive. CHADL antibody is predicted to not cross-react with Chondroadherin protein.

• Symbol:

  CHADL

• NCBI Official Name:

  Chondroadherin-like

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Tillgren V, Ho JC, Onnerfjord P, et al. The novel small leucine-rich protein chondroadherin-like (CHADL) is expressed in cartilage and modulates chondrocyte differentitation. J. Biol. Chem. 2015; 290:918-25.

• Background Reference 02:

  Neame PJ, Sommarin Y, Boynton RE, et al. The structure of a 38-kDa leucine-rich protein (chondroadherin) isolated from bovine cartilage. J. Biol. Chem. 1994; 269:21547-54.

• Other Product Names:

  Chondoadherin-like protein, SLRR4B

• Tested Applications:

  ELISA, WB, IHC, IF

• Protein ID:

  194440719

• Physical Properties:

  Liquid