Products for Research Use Only
RegisterLogin

NINJ1 Antibody

CAT: 0223-7967-01Size: 0.02 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-7967-01Size:0.02 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Ninjurin-1 (NINJ1) is a homophilic adhesion molecule that is strongly induced in dorsal root ganglion (DRG) and Schwann cells following nerve injury and promotes neurite outgrowth of DRG neurons (1,2), suggesting that NINJ1 may play a role in nerve regeneration. NINJ1 is transcriptionally regulated by p53 and is induced by DNA damage in a p53-dependent manner. A deficiency of NINJ1 increases p53 expression, suppresses cell proliferation, but enhances apoptosis and premature senescence in a p53-dependent manner as well as radiation-induced cell mortality (3) .
NCBI Gene ID
4814
Swiss Prot
Q92982
Accession Number
NP_004139
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Apoptosis
Purification
NINJ1 antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL
Buffer
NINJ1 antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
NINJ1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
NINJ1 antibody is human, mouse and rat reactive.
Symbol
NINJ1
NCBI Official Name
Ninjurin 1
NCBI Organism
Homo sapiens
Background Reference 01
Araki T and Milbrandt J. Ninjurin, a novel adhesion molecule, is induced by nerve injury and promotes axonal growth. Neuron 1996; 17:353-61.
Background Reference 02
Araki T, Zimonjic DB, Popescu NC, et al. Mechanism of homophilic binding mediated by ninjurin, a novel widely expressed adhesion molecule. J. Biol. Chem. 1997; 212:21373-80.
Background Reference 03
Cho SJ, Rossi A, Jung YS, et al. Ninjurin1, a target of p53, regulates p53 expression and p53-dependent cell survival, sensecence, and radiation-induced mortality. Proc. Natl. Acad. Sci. USA 2013; 110:9362-7.
Other Product Names
NINJ1 Antibody: NIN1, NINJURIN, Ninjurin-1, Nerve injury-induced protein 1
Tested Applications
ELISA, IHC-P, IF
Protein ID
148922911
Physical Properties
Liquid

Related Products

CatalogName
7967PNINJ1 Peptide
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
62-828Neprilysin Antibody
61-580CAPZB Antibody
55-580HCG_2024410 Antibody
30-580ACPT Antibody
19-580FABP3 Antibody
15-580POMGNT2 Antibody

Alternative Products

CatalogName
MBS7006276-01NINJ1 Antibody
ANT-13452-50ugNINJ1 Polyclonal Antibody
GTR17902481-01NINJ1 Antibody (FITC)
GTR17902480-01NINJ1 Antibody (HRP)
GTR18224077NINJ1/Ninjurin Antibody
CSB-CL856441HU1NINJ1

Popular Products