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UCP1 Antibody

CAT: 0223-7697-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-7697-01Size:0.02 mg
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Background
The mitochondrial brown fat uncoupling protein 1 (UCP1) is a member of the family of mitochondrial anion carrier proteins (MACP) (1) . UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells (1) . UCP1 is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat (1) .
NCBI Gene ID
7350
Swiss Prot
P25874
Accession Number
NP_068605
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity
Purification
UCP1 antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1303 - Human Brain Tissue Lysate
Concentration
1 mg/mL
Buffer
UCP1 antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
UCP1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
UCP1 antibody is human, mouse and rat reactive.
Symbol
UCP1
Positive Control 2
Cat. No. 10-201 - Human Liver Tissue Slide
NCBI Official Name
Uncoupling protein 1 (mitochondrial, proton carrier)
NCBI Organism
Homo sapiens
Background Reference 01
Rial E, Gonzalez-Barroso MM, Fleury C, et al. The structure and function of the brown fat uncoupling protein UCP1: current status. Biofactors 1998; 8:209-19.
Other Product Names
UCP1 Antibody: UCP, SLC25A7, UCP, Mitochondrial brown fat uncoupling protein 1, Solute carrier family 25 member 7, UCP 1
Tested Applications
ELISA, WB, IHC-P
Protein ID
11225256
Physical Properties
Liquid

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