Products for Research Use Only
RegisterLogin

DNM1L Antibody

CAT: 0223-7603-01Size: 0.02 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-7603-01Size:0.02 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The Dynamin-1-like protein (DNM1L) is a member of the dynamin superfamily of GTPases (1) . DNM1L mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis (2) . Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF) (3) .
NCBI Gene ID
10059
Swiss Prot
O00429
Accession Number
NP_036192
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis
Purification
DNM1L antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1201 - HeLa Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Rat: (100%), Bovine: (100%)
Buffer
DNM1L antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
DNM1L antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
DNM1L antibody is human and mouse reactive. At least four isoforms of DNM1L are known to exist; this antibody will detect the two longest isoforms.
Symbol
DNM1L
Positive Control 2
Cat. No. 17-001 - HeLa Cell Slide
NCBI Official Name
Dynamin 1-like
NCBI Organism
Homo sapiens
Background Reference 01
Shin HW, Shinotsuka C, Torii S, et al. Identification and subcellular localization of a novel mammalian dynamin-related protein homologous to yeast Vps1p and Dnm1p. J. Biochem. 1997; 122:525-30.
Background Reference 02
Frank S, Gaume B, Bergmann-Leitner ES, et al. The role of dynamin-related protein1, a mediator of mitochondrial fission, in apoptosis. Dev. Cell 2001; 1:515-25.
Background Reference 03
Reddy PH, Reddy TP, Manczak M, et al. Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases. Brain Res. Rev. 2011; 67:103-18.
Other Product Names
DNM1L Antibody: DLP1, DRP1, DVLP, EMPF, DYMPLE, HDYNIV, DLP1, Dynamin-1-like protein, Dynamin family member proline-rich carboxyl-terminal domain less
Tested Applications
ELISA, WB, ICC, IF
Protein ID
171460914
Physical Properties
Liquid

Related Products

CatalogName
7603PDNM1L Peptide
18-861DNM1 Antibody
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
62-828Neprilysin Antibody
61-580CAPZB Antibody
55-580HCG_2024410 Antibody
30-580ACPT Antibody
19-580FABP3 Antibody

Alternative Products

CatalogName
GTR18145984DNM1L Antibody

Popular Products