KAT5 Antibody

• Background :

  KAT5 Antibody: KAT5 belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and non-histone proteins. KAT5 has been shown to play a role in DNA repair and apoptosis and is thought to play an important role in signal transduction and autophagy.

• NCBI Gene ID :

  10524

• Swiss Prot :

  Q92993

• Accession Number :

  NP_874369

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Autophagy

• Purification :

  KAT5 Antibody is affinity chromatography purified via peptide column.

• Positive Control :

  Cat. No. 1303 - Human Brain Tissue Lysate

• Concentration :

  1 mg/mL

• Buffer :

  KAT5 Antibody is supplied in PBS containing 0.02% sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  KAT5 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

• Fragment :

  IgG

• Specificity :

  Multiple isoforms of KAT5 are known to exist.

• Symbol :

  KAT5

• NCBI Official Name :

  K (lysine) acetyltransferase 5

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Kamine J, Elangovan B, Subramanian T, et al. Identification of a cellular protein that specifically interacts with the essential cysteine region of the HIV-1 Tat transactivator. Virology 1996; 216:357-66.

• Background Reference 02 :

  Kimura A and Horikoshi M. Tip60 acetylates six lysines of a specific class of core histones in vitro. Genes Cells 1998; 3:789-800.

• Background Reference 03 :

  Ikura T, Ogryzko VV, Grigoriev M, et al. Involvement of the TIP70 histone acetylase complex in DNA repair and apoptosis. Cell 2000; 102:463-73.

• Background Reference 04 :

  Lin SY, Li TY, Liu Q, et al. GSK3-TIP60-ILK1 signaling pathway links growth factor deprivation to autophagy. Science 2012; 336:477-81.

• Other Product Names :

  KAT5 Antibody: TIP, ESA1, PLIP, TIP60, cPLA2, HTATIP, ZC2HC5, HTATIP1, Histone acetyltransferase KAT5, 60 kDa Tat-interactive protein, Tip60

• Tested Applications :

  ELISA, WB, IHC-P, IF

• Protein ID :

  36287069

• Physical Properties :

  Liquid