Products for Research Use Only
RegisterLogin

ANG Antibody

CAT: 0223-6983-01Size: 0.02 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-6983-01Size:0.02 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
ANG Antibody: Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels. ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton. ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9) . Angiogenin is a genetic link between ALS and PD.
NCBI Gene ID
283
Swiss Prot
P03950
Accession Number
NP_001136
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
ANG Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1464 - Rat Liver Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Horse: (75%)
Buffer
ANG Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
ANG antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
16 kDa
Fragment
IgG
Specificity
Two alternatively spliced transcript variants have been observed.
Symbol
ANG
Positive Control 2
Cat. No. 10-201 - Human Liver Tissue Slide
NCBI Official Name
Angiogenin, ribonuclease, RNase A family, 5
NCBI Organism
Homo sapiens
Background Reference 01
Moroianu J and Riordan JF. Identification of the nucleolar targeting signal of human angiogenin. Biochem. Biophys. Res. Commun. 1994; 203:1765-72.
Background Reference 02
Hu G, Riordan JF, and Vallee BL. Angiogenin promotes invasiveness of cultured endothelial cells by stimulation of cell-associated proteolytic activities. Proc. Natl. Acad. Sci. USA 1994; 91:12096-100.
Background Reference 03
Pyatibratov MG and Kostyukova AS. New insights into the role of angiogenin in actin polymerization. Int. Rev. Cell. Mol. Biol. 2012; 295:175-98.
Background Reference 04
Li S, Ibaragi S, and Hu GF. Angiogenin as a molecular target for the treatment of prostate cancer. Curr. Cancer Ther. Rev. 2011; 7:83-90.
Other Product Names
ANG Antibody: ALS9, RAA1, HEL168, RNASE4, RNASE5, Angiogenin, Ribonuclease 5, RNase 5
Tested Applications
ELISA, WB, IF
Protein ID
4557313
Physical Properties
Liquid

Related Products

CatalogName
6983PANG Peptide
40-540-002mgANG-2 Recombinant Protein
40-540-01ANG-2 Recombinant Protein
40-540-0005mgANG-2 Recombinant Protein
40-229-0005mgANG-1 Recombinant Protein
40-229-002mgANG-1 Recombinant Protein
40-229-01ANG-1 Recombinant Protein
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody

Alternative Products

CatalogName
MBS8529199-01H2B Antibody Antibody
MBS8513599-01CD11b Antibody Antibody
MBS850197-01Antibody to IGFBP2 Antibody
DF8746-01ASAP1 antibody Antibody
E36403ZNF98 Antibody Antibody
GWB-250026Lck antibody Antibody
E8M1007-4HSP60 Antibody Antibody
MBS9403836-01SZT2 Antibody Antibody
LSMab09882anti-Antibody^Polyclonal antibody control antibody
GWB-5C6547MAD1L1 antibody [9B10] Antibody

Popular Products