DBX2 Antibody

• Background:

  DBX2 Antibody: DBX2 is a member of the developing brain homeobox (DBX) protein family, but while the related protein DBX1 is expressed in various regions of the developing brain, DBX2 shows a more restricted pattern of expression in the brain, and is also expressed in some mesenchymal cells such as limb buds and tooth germs. It is thought that DBX1 and DBX2 promote the development of a subset of interneurons, some of which help mediate left-right coordination of locomotor activity. In Xenopus, DBX2 is involved in primary neurogenesis and early neural plate patterning, and is thought to act as a cross-repressive partner of NKX6-2 in the patterning of the ventral neural tube.

• NCBI Gene ID:

  440097

• Swiss Prot:

  Q6ZNG2

• Accession Number:

  NP_001004329

• Host:

  Rabbit

• Reactivity:

  Human

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Stem Cell

• Purification:

  DBX2 Antibody is affinity chromatography purified via peptide column.

• Positive Control:

  Cat. No. 1305 - Human Kidney Tissue Lysate

• Concentration:

  1 mg/mL

• Buffer:

  DBX2 Antibody is supplied in PBS containing 0.02% sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  DBX2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Fragment:

  IgG

• Specificity:

  DBX2 antibody is human specific. At least two isoforms of DBX2 are known to exist; this antibody will only detect the shortest isoform.

• Symbol:

  DBX2

• Positive Control 2:

  Cat. No. 10-401 - Human Kidney Tissue Slide

• NCBI Official Name:

  Developing brain homeobox 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Shoji H, Ito T, Wakamatsu Y, et al. Regionalized expression of the Dbx family homeobox genes in the embryonic CNS of the mouse. Mech. Dev. 56:25-39.

• Background Reference 02:

  Lacin H, Zhu Y, Wilson BA, et al. Dbx mediates neuronal specification and differentiation through cross-repressive, lineage-specific interactions with eve and hb9. Development 2009; 136:3257-66.

• Background Reference 03:

  Ma P, Zhao S, Zeng W, et al. Xenopus Dbx2 is involved in primary neurogenesis and early neural plate patterning. Biochem. Biophys. Res. Commun. 2011; 412:170-4.

• Other Product Names:

  DBX2 Antibody: Homeobox protein DBX2, Developing brain homeobox protein 2

• Tested Applications:

  ELISA, WB, IHC-P, IF

• Protein ID:

  116174748

• Physical Properties:

  Liquid