DBX1 Antibody

CAT: 0223-6455-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#:0223-6455-01Size:0.02 mg
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Background
DBX1 Antibody: DBX1 is implicated in patterning the central nervous system during embryogenesis. DBX1 homeodomain transcription factor is expressed in progenitors which are critical in establishing cell fate allocation and cell diversity. DBX1 has a key role in regulating the distinct phenotypic features that distinguish two major classes of ventral interneurons, V0 and V1 neurons. DBX1-derived neurons are essential for the transgenic expression and generation of respiratory behavior both in vitro and in vivo.
NCBI Gene ID
120237
Swiss Prot
A6NMT0
Accession Number
NP_001025036
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
DBX1 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1405 - Mouse Kidney Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (87%)
Buffer
DBX1 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
DBX1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
BX1 antibody is predicted to not cross-react with other DBX protein family members
Symbol
DBX1
Positive Control 2
Cat. No. 10-401 - Human Kidney Tissue Slide
NCBI Official Name
Developing brain homeobox 1
NCBI Organism
Homo sapiens
Background Reference 01
Griveau A, Borello U, Causeret F, et al. A novel role for Dbx1-derived Cajal-Retzius cells in early regionalization of the cerebral cortical neuroepithelium. PLoS Biol. 2010; 8 (7) :e1000440
Background Reference 02
Causeret F, Ensini M, Teissier A, et al. Dbx1-expressing cells are necessary for the survival of the Mammalian anterior neural and craniofacial structures. PLoS One 2011; 6:e19367.
Background Reference 03
Pierani A, Moran-Rivard L, Sunshine MJ, et al. Control of interneuron fate in the developing spinal cord by the progenitor homeodomain protein Dbx1. Neuron 2001; 29:367-84
Background Reference 04
Gray PA, Hayes JA, Ling GY, et al. Developmental origin of preBotzinger complex respiratory neurons. J. Neurosci. 2010; 30:14883-95.
Other Product Names
DBX1 Antibody: Homeobox protein DBX1, Developing brain homeobox protein 1
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
304434796
Physical Properties
Liquid

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