TFEB Antibody

CAT: 0223-6801-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#:0223-6801-01Size:0.02 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
TFEB Antibody: The Transcription factor EB (TFEB) is a member in the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors. Recent studies have shown that lysosomal biogenesis is regulated by TFEB, which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1. Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes.
NCBI Gene ID
7942
Swiss Prot
P19484
Accession Number
NP_009093
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Autophagy
Purification
TFEB Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1203 - A549 Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Mouse: (100%)
Buffer
TFEB Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
TFEB antibody can be stored at 4˚ C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Symbol
TFEB
Positive Control 2
Cat. No. 10-101 - Human Lung Tissue Slide
NCBI Official Name
Transcription factor EB
NCBI Organism
Homo sapiens
Background Reference 01
Carr CS and Sharp PA. A helix-loop-helix protein related to the immunoglobulin E box-binding proteins. Mol. Cell Biol. 1990; 10:4384-8.
Background Reference 02
Davis IJ, Hsi BL, Arroyo JD, et al. Cloning of an alpha-TFEB fusion in renal tumors harboring the t (6;11) (p21; q13) chromosome translocation. Proc. Natl. Acad. Sci. USA 2003; 100:6051-6.
Background Reference 03
Sardiello M, Palmieri M, di Ronza A, et al. A gene network regulating lysosomal biogenesis and function. Science 2009; 325:473-7.
Background Reference 04
Pena-Llopis S, Vega-Rubin-de-Celis S, Schwartz JC, et al. Regulation of TFEB and V-ATPases my mTORC1. EMBO J. 2011; 30:3242-58
Other Product Names
TFEB Antibody: TCFEB, BHLHE35, ALPHATFEB, Transcription factor EB, Class E basic helix-loop-helix protein 35, bHLHe35
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
24307933
Physical Properties
Liquid

Related Products

CatalogName
45-159PTFEB Peptide
6801PTFEB Peptide
46-482TFE3 Antibody
46-483TFEC Antibody
60-561TFEC Antibody
XW-7695TFE3 Antibody
27-535TFEC Antibody
79-650TFE3 Antibody
31-268TFE3 Antibody
59-796TFE3 Antibody

Alternative Products

CatalogName
MBS8513851-01TFEB Antibody

Popular Products