RILPL1 Antibody

CAT: 0223-6495-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#:0223-6495-01Size:0.02 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
RILPL1 Antibody: While the function of the Rab interacting lysosomal protein-like 1 (RILPL1) remains unknown, the homologous protein RILP is a small GTPase that controls transport to endocytic compartments, suggesting RILPL1 may have similar functions. However, overexpression of RILP caused enlarged lysosomes that are more centrally located in the cell, while overexpression of RILPL1 had no visible effect on the location or morphology of lysosomes.
NCBI Gene ID
353116
Swiss Prot
Q5EBL4
Accession Number
AAH89444
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
RILPL1 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1473 - Rat Cerebellum Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (94%)
Buffer
RILPL1 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
RILPL1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
At least three isoforms of RILPL1 are known to exist; this antibody will detect the two shorter isoforms. RILPL1 antibody is predicted to not cross-react with RILP.
Symbol
RILPL1
NCBI Official Name
Rab interacting lysosomal protein-like 1
NCBI Organism
Homo sapiens
Background Reference 01
Cantalupo G, Alifano P, Roberti V, et al. Rab-interacting lysosomal protein (RILP) : the Rab7 effector required for transport to lysosomes. EMBO J. 2001; 20:683-93
Background Reference 02
Wang T, Wong KK, and Hong W. A unique region of RILP distinguishes it from its related proteins in its regulation of lysosomal morphology and interaction with Rab7 and Rab34. Mol. Biol. Cell 2004; 15:815-26
Other Product Names
RILPL1 Antibody: RLP1, GOSPEL, RLP1, RILP-like protein 1, Rab-interacting lysosomal-like protein 1
Tested Applications
ELISA, WB, IF
Protein ID
195947382
Physical Properties
Liquid

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