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WDR92 Antibody

CAT: 0223-5883-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-5883-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
WDR92 Antibody: WD40 repeats are a common structural module in eukaryotic proteins, and proteins containing WD40 domains have a wide range of functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription. One such protein, WDR92, also known as monad, contains two WD40 repeats is widely expressed in human tissues, especially testis. Overexpression of this protein or its binding partner RNA polymerase II-associated protein 3 (RPAP3) potentiated apoptosis and caspase-3 activation induced by TNF-α and cycloheximide, suggesting that WDR92, together with RPAP3, may function as a novel modulator of apoptosis.
NCBI Gene ID
116143
Swiss Prot
Q96MX6
Accession Number
NP_612467
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis
Purification
WDR92 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1305 - Human Kidney Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (100%)
Buffer
WDR92 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
WDR92 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Symbol
WDR92
Positive Control 2
Cat. No. 11-701 - Human Testis Tissue Slide
NCBI Official Name
WD repeat domain 92
NCBI Organism
Homo sapiens
Background Reference 01
Saeki M, Irie Y, Ni L, et al. Monad, a WD40 repeat protein, promotes apoptosis induced by TNF-alpha. Biochem. Biophys. Res. Commun.2006; 342:568-72.
Background Reference 02
Itsuki Y, Saeki M, Nakahara H, et al. Molecular cloning of novel Monad binding protein containing tetratricorticopeptide repeat domains. FEBS Lett.582:2365-70.
Other Product Names
WDR92 Antibody: WD repeat-containing protein 92, WD repeat-containing protein Monad
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
24308444
Physical Properties
Liquid

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