Products for Research Use Only
RegisterLogin

MMS21 Antibody

CAT: 0223-5759-01Size: 0.02 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-5759-01Size:0.02 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
MMS21 Antibody: MMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression; this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2.
NCBI Gene ID
286053
Swiss Prot
Q96MF7
Accession Number
NP_775956
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
MMS21 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1210 - HEK293 Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (80%)
Buffer
MMS21 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
MMS21 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Symbol
NSMCE2
NCBI Official Name
Non-SMC element 2, MMS21 homolog (S. cerevisiae)
NCBI Organism
Homo sapiens
Background Reference 01
Potts PR and Yu H. Human MMS21/NSE2 is a SUMO ligase required for DNA repair. Mol. Cell. Biol. 2005; 25:7021-32.
Background Reference 02
Behlke-Steinert S, Touat-Todeschini L, Skoufias DA, et al. SMC5 and MMS21 are required for chromosome cohesion and mitotic progression. Cell Cycle 2009; 8:2211-8.
Background Reference 03
Bermudez-Lopez M, Ceschia A, de Piccoli G, et al. The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages. Nucleic Acids Res. 2010; 38:6502-12.
Other Product Names
MMS21 Antibody: NSE2, MMS21, ZMIZ7, C8orf36, E3 SUMO-protein ligase NSE2, MMS21 homolog, hMMS21
Tested Applications
ELISA, WB
Protein ID
27734761
Physical Properties
Liquid

Related Products

CatalogName
5759PMMS21 Peptide
45-892MMS2 Antibody
45-892PMMS2 Peptide
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
62-828Neprilysin Antibody
61-580CAPZB Antibody
55-580HCG_2024410 Antibody
30-580ACPT Antibody

Alternative Products

CatalogName
MBS9404775-01MMS21 Antibody
GTR18216903-01Rabbit MMS21 Antibody
APR06634GPolyclonal MMS21 Antibody
MBS9238860-01NSE2/MMS21 Polyclonal Antibody
A06693Anti-MMS21 NSMCE2 Antibody
RQ8343NSMCE2 Antibody / NSE2 / MMS21
GTR18210089MMS21 (N) Antibody, Rabbit Polyclonal
GTR18420924NSE2/MMS21 Rabbit Polyclonal Antibody (BF594)
GTR17811788NSE2/MMS21 Rabbit Polyclonal Antibody (Cy3)
GTR18210091MMS21 (C) Antibody, Rabbit Polyclonal

Popular Products