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MMS21 (C) Antibody, Rabbit Polyclonal

CAT: 0013-GTR18210091Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18210091Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to MMS21.MMS21 is also known as E3 SUMO-protein ligase NSE2E3, which is a SUMO-protein ligasecomponent of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks byhomologous recombination. The complex may promote sister chromatid homologous recombinationby recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. MMS21 acts as a E3 ligasemediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesincomponents RAD21 and STAG2. The SUMO protein-ligase activity of MMS21 is required for theprevention of DNA damage-induced apoptosis by facilitating DNA repair.
Product Name Alternative
Anti-MMS21 antibody, anti-E3 SUMOprotein ligase NSE2 antibody, anti-MMS21 homolog antibody, anti-hMMS21 antibody, anti-Nonstructural maintenance of chromosomes element 2 homolog antibody, anti-NonSMC element 2 homolog antibody, anti-NSMCE2 antibody, anti-C8orf36 antibody, anti-MMS21 antibody
UniProt
Q96MF7
Reactivity
Human
Immunogen
C-terminal region of human MMS21
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cancer, DNA Damage, Epigenetics
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
28
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3

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